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The Suv420h histone methyltransferases regulate PPAR

Obesity and its associated metabolic abnormalities have become a global emergency with considerable morbidity and mortality Epidemiologic and animal model data suggest an epigenetic contribution to obesity Nevertheless, the cellular and molecular mechanisms through which epigenetics contributes to the development of obesity remain to be elucidated Suv420h1 and Suv420h2 are histone ....

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Magalir Mattum

Magalir Mattum (transl Ladies Only) is a 1994 Tamil-language Indian satirical film directed by Singeetam Srinivasa Rao and produced by Kamal Haasan The film stars Nassar, Revathi, Urvashi and Rohini in the lead rol The screenplay was written by Crazy Mohan based on a story by Kamal that was inspired by the American film 9 to 5 (1980)...

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Resolving TYK2 locus genotype

Determining the biological consequences of the thousands of genetic variants that contribute to common diseases for the purpose of improving health care is challenging Genetic variants that influence autoimmune diseases have been identified in the tyrosine kinase 2 ( TYK2 ) gene, but conflicting evidence regarding their biological impact obscures the therapeutic potential of TYK2 By ....

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